NGT direct U.P. govt. to take remedial action

first_imgThe National Green Tribunal (NGT) has directed the Uttar Pradesh government to take steps in curbing water pollution around industrial areas in the State.Following a report furnished by the Uttar Pradesh Pollution Control Board stating that industrial effluents are contaminating the Hindon river, a Bench headed by NGT Chairperson Adarsh Kumar Goel said, “When industrial areas are set up, requisite infrastructure for scientific discharge of effluents is not being developed. Let this aspect be considered by the Chief Secretary, U.P., and remedial measures be taken.”The Bench added that the remedial measures to be taken are in respect of areas that are “already set up as well as the areas which may be set up later” as industrial areas.Taking into consideration an action taken report submitted by the State pollution control board, the Bench observed, “…(the report) acknowledges that industrial effluents and sewage are being discharged into the drain connecting Hindon river which is broken at many places. Overflow of the effluents is collected in vacant plots.”“The UPPCB may monitor the compliance of the environmental norms and furnish a further report to the tribunal within three months,” the bench said.last_img read more

Cliff Hodge return a shot in the arm for Meralco

first_imgNEXT BLOCK ASIA 2.0 introduces GURUS AWARDS to recognize and reward industry influencers Read Next 2 ‘newbie’ drug pushers fall in Lucena sting Meralco’s Cliff Hodge. Photo by Tristan Tamayo/INQUIRER.netCliff Hodge reminded the Meralco Bolts what they had been missing in their first four games.Hodge made his season debut on Wednesday and he returned at the best possible time with the Bolts on a three-game skid coming into the game.ADVERTISEMENT “Nobody’s happier than me to see him (Hodge) back. I mentioned earlier about the lack of effort against TNT and we seemed to have a low energy level against TNT,” Meralco head coach Norman Black said.“We all know that’s [what] Cliff is [all] about. He’s about energy and effort and probably just his presence really helped us a great deal tonight because he does give a lot of effort out there, particularly on the defensive end.”FEATURED STORIESSPORTSWATCH: Drones light up sky in final leg of SEA Games torch runSPORTSLillard, Anthony lead Blazers over ThunderSPORTSMalditas save PH from shutoutThe 29-year-old Hodge made immediate impact the moment he was fielded into the game at the 2:30 mark of the first quarter. He grabbed an offensive rebound just 36 seconds in that led to a basket by his teammate Bryan Faundo.Hodge finished with eight points on 4-of-4 shooting from the field with six rebounds, three assists and a steal. Four of his boards were offensive rebounds. Police teams find crossbows, bows in HK university PLAY LIST 01:29Police teams find crossbows, bows in HK university01:35Panelo suggests discounted SEA Games tickets for students02:49Robredo: True leaders perform well despite having ‘uninspiring’ boss02:42PH underwater hockey team aims to make waves in SEA Games01:44Philippines marks anniversary of massacre with calls for justice01:19Fire erupts in Barangay Tatalon in Quezon City LATEST STORIES Slow and steady hope for near-extinct Bangladesh tortoises Alex Cabagnot sidelined with foot injury, no surgery needed It was an all-around effort from Hodge, doing a little bit of everything in just 19 minutes of play despite still not being 100 percent healthy yet.“I’m pretty tired, but I’m happy that we got the win so that’s all that matters,” he said after helping Meralco get back on the winning track with a 105-76 rout of Kia.“Yeah, I’m really out of shape. I haven’t played basketball in about three months and I’ve only practiced in like two days,” added Hodge, who went under the knife to remove bone spurs in his ankles. “I just need to get back in shape. Actually, my ankle still hurt so I’m just playing through that until it gets better.”Hodge was supposed to be out for at least two more weeks, but with Meralco struggling he knew he would be of great help to his team especially with Ranidel de Ocampo still out with a calf injury.“I know that we needed some wins so I said if I can go up and down [even if] I’m not 100 percent but I mean, I can go out there on defense. I just decided to come back and try and do whatever I can for my team.”ADVERTISEMENTcenter_img Kammuri turning to super typhoon less likely but possible — Pagasa Globe Business launches leading cloud-enabled and hardware-agnostic conferencing platform in PH John Lloyd Cruz a dashing guest at Vhong Navarro’s wedding Brace for potentially devastating typhoon approaching PH – NDRRMC Don’t miss out on the latest news and information. Typhoon Kammuri accelerates, gains strength en route to PH View comments MOST READlast_img read more

Claressa Shields in another boxing 1st on Showtime

first_imgPDEA chief backs Robredo in revealing ‘discoveries’ on drug war LATEST STORIES Sports Related Videospowered by AdSparcRead Next MOST READ US judge bars Trump’s health insurance rule for immigrants ‘We are too hospitable,’ says Sotto amid SEA Games woes Private companies step in to help SEA Games hosting UAAP men’s volleyball: NU turns back La Salle, Adamson sweeps UE Showtime announced Tuesday that the episodes will premiere March 29 and April 5 on SHO Sports YouTube and Facebook pages. Shields and Hammer will fight for the undisputed middleweight championship on April 13, broadcast live on Showtime from Atlantic City, New Jersey.The episodes will show Shields preparing at the U.S. Olympic Training Center in Colorado Springs, Colorado, and Hammer training in Seefeld, Austria.FEATURED STORIESSPORTSPrivate companies step in to help SEA Games hostingSPORTSUrgent reply from Philippine ‍football chiefSPORTSPalace wants Cayetano’s PHISGOC Foundation probed over corruption chargesUndefeated Shields (8-0, 2 KOs) and Hammer (24-0, 11 KOs) were supposed to fight on Nov. 17, but Hammer postponed it because of illness.Showtime Sports President Stephen Espinoza says the fight highlights “two of the elite athletes in boxing” in the network’s 10th women’s bout since 2017. That year, Shields became the first woman to headline a fight card on premium cable. Undefeated women’s middleweight world champion Claressa Shields, second from left, is handed one of her three title belts as prepares to pose with her world champion opponent Christina Hammer, far right, during a press conference to preview their upcoming fight, Tuesday Feb. 26, 2019, in New York. Shields and Hammer will showdown for the undisputed women’s middleweight world championship in a unification bout on Saturday, April 13 in Atlantic City, N.J. (AP Photo/Bebeto Matthews)NEW YORK — Claressa Shields is participating in another first for women’s boxing.The two-time Olympic gold medalist and Christina Hammer will be featured in “All Access” episodes on Showtime Sports’ social media platforms.ADVERTISEMENT Don’t miss out on the latest news and information. Grace Poe files bill to protect govt teachers from malicious accusations PH underwater hockey team aims to make waves in SEA Games PLAY LIST 02:42PH underwater hockey team aims to make waves in SEA Games01:44Philippines marks anniversary of massacre with calls for justice01:19Fire erupts in Barangay Tatalon in Quezon City01:07Trump talks impeachment while meeting NCAA athletes02:49World-class track facilities installed at NCC for SEA Games02:11Trump awards medals to Jon Voight, Alison Krauss Urgent reply from Philippine ‍football chief SEA Games hosting troubles anger Duterte Oil plant explodes in Pampanga town View commentslast_img read more

Prefers to remain simple by choice, says Parrikar

first_imgMumbai, Sep 16 (PTI) Simplicity brings comfort for Defence Minister Manohar Parrikar who still prefers to use once ubiquitous ambassador car in Delhi in the era of SUVs and also feels “jittery” when surrounded by security personnel who are part of his entourage. Recounting his days as Goa chief minister, Parrikar said he prefers to stay simple by choice. “Even after becoming Defence minister, I travel in an ambassador (car) in New Delhi whose doors get jammed from time to time and even the car breaks down thrice a day. But, simplicity is my comfort and I prefer to remain simple by choice. I get jittery when there are policemen surrounding me (for security),” the minister said. The technocrat-cum-politician was addressing a gathering here on the 43rd anniversary of GIANTS International Awards. Every year, GIANTS Felicitates prominent personalities who have contributed immensely to the society in the field of business and industry, education , medicine, journalism, films, music, sports and social services. “Once when I was Goa CM, a party worker had called me to his house for tea. I went to his house and fulfilled my commitment. Next day, when I called him if he was satisfied, he replied that he indeed was but asked me why did I not bring my pilot vehicles and escorts along with me. “I asked him if my coming wasnt enough, to which he replied that even though I had come, nobody in his village knew that the CM had visited his house,” Parrikar said evoking a ripple of laughter. Parrikar said one should be proud of knowledge that India has given to the world even as he encouraged the audience to work towards “immortality.” The former IITian said people should understand the vision of Prime Minister Narendra Modi. “At first, when Modi-ji was the CM of Gujarat, I only knew him as a person with a lot of energy to do the right things. From the last 10 months or so, I have started knowing him as a person with immense vision,” he said. Parrikar said initiatives launched by PM like Beti Bachao Beti Padhao and Selfie with daughters have played a major role in increasing the ratio of girl child in many places. PTI MM NSK RG SRElast_img read more

Milan banned from Europa League for one year after FFP breach

first_imgReuse this content Read more Their place in the Europa League is now likely to go to Torino, who finished seventh in Serie A last season, which means their season will start with the final qualifying round for the competition’s group stages on July 25. Uefa initially gave Milan a two-year FFP ban last summer but the club successfully appealed against that sanction at Cas, only for the seven-time European champions to be referred to Uefa’s financial watchdog again in April. Under Uefa’s rules, clubs are not allowed to make losses of more than €30m (£27m) over three seasons, a cap Uefa believed Milan breached between 2015-17 when they spent 200million on transfers, with more spending in 2018, as well.But Milan managed to persuade sport’s highest court that their finances would improve under the ownership of American hedge fund Elliott Management Corporation, which assumed control of the club last summer when former owner Li Yonghong missed a repayment on the loan he had taken to buy the club in 2017. That Cas decision gave them until June 2021 to balance their books or receive an automatic one-year ban from European club football. But April’s referral for a second FFP breach could have seen the club banned from Europe for two years, which clearly forced Milan back to the negotiating table where they have agreed to serve a one-year ban now while they tidy up their finances under the direction of former Arsenal chief executive Ivan Gazidis. Uefa Share via Email Milan Milan has struck a deal with Uefa to serve a one-year ban from European football for breaching the governing body’s financial fair play rules, the Court of Arbitration for Sport (Cas) has confirmed.The agreement means Milan will not take their place in next season’s Europa League and Uefa will end its proceedings against the Italian club for overspending between 2016-18 – the second three-year accounting period in a row that had got them in hot water with Uefa. Europa League Share on Messenger Share on Twitter news Share on Pinterest Share on LinkedIn Topics Manchester City lodge appeal with Cas over Uefa’s FFP referral Share on WhatsApp Share on Facebooklast_img read more

Senate Approves New Fisheries Act

first_imgA new Fisheries Act, aimed at further safeguarding the local sector, was passed in the Senate on October 12.The Bill, which will replace the Fishing Industry Act of 1975, will establish the legal and regulatory framework that creates the enabling environment for the sector’s sustainable growth.This includes ramping up measures to tackle poaching and unregulated fishing in Jamaican waters.The new legislation will facilitate the establishment of a proper licensing authority equipped with the requisite provisions and safeguards that ensure transparency.Additionally, a new category of licences will also be instituted. These include a local fishing vessel licence; foreign fishing vessel licence; commercial fishing licence; recreational fishing licence; high seas fishing vessel licence; commercial aquaculture licence; and a licence to operate a commercial aquaculture facility.Piloting the Bill, Leader of Government Business and Minister of Foreign Affairs and Foreign Trade, Senator the Hon. Kamina Johnson Smith, said the Bill seeks to ensure that the industry is modernised and is consistent with international best practices and norms.It also seeks to provide for and promote the effective management and sustainable development of fisheries and aquaculture.Senator Johnson smith noted that one of the main features is the formation of the various administrative bodies which will include: a new national fisheries authority, the national fisheries advisory council, and the appeals tribunal.“The fisheries authority will have the responsibility to manage, develop, regulate the fisheries and aquaculture industries. Its functions will include the granting, variation, suspension and cancellation of licences and authorisations, so it will be creating a much more transparent and effective institutional mechanism for licensing,” she said.Conservative estimates indicate that Jamaica loses in excess of US$10 million annually from poaching, particularly of spiny lobsters on the Pedro Banks and  US$1.3 million on conch.In 2017, there were approximately 25,000 registered fishers in the country.The revised legislation makes it mandatory for all persons fishing in Jamaican waters to have a valid licence issued by the relevant authority.Persons fishing in a pond situated on a single private property and persons fishing with a line from the seashore have been exempted from obtaining a licence.Under the legislation, fisherfolks who fail to carry upon his person the prescribed fishing licence while he is fishing can be fined a maximum of $10,000. It also provides a maximum fine of $50,000 for failure to report a fishing vessel that is lost, becomes permanently unserviceable and is no longer seaworthy.It also imposes a fine for failure to stow fishing gear in a prescribed manner; failure to take all reasonable measures to ensure the safety of a fishery inspector; or for leaving decayed or dying fish in any net or other fishing equipment.The Bill was passed with 25 amendments.last_img read more

UN health agency expands programme to fight neglected tropical diseases

This expansion is possible thanks to a renewed collaboration with sanofi-aventis, the world’s number 3 pharmaceutical company, which has agreed to donate medicines and financial support worth $25 million over five years to the UN World Health Organization (WHO).This collaboration builds on a previous agreement in 2001 between WHO and Aventis (now sanofi-aventis) to prevent deaths due to sleeping sickness, a parasitic disease spread by the bite of the tsetse fly that is fatal if not treated and causes bouts of fever, headaches, joint pains and itching, and in later stages confusion, sensory disturbances and poor coordination, including disturbance of the sleep cycle.“This project shows the power of collaboration to make a positive difference in the lives of poor people,” WHO Acting Director-General Anders Nordström said. “By actively seeking out people who show the early symptoms of these diseases, we can ensure that they get the treatment they need before their symptoms worsen.”Sanofi-aventis will donate $5 million in drugs to treat sleeping sickness and a further $20 million in financial support for the control of neglected tropical diseases, such as leishmaniasis, a skin disease that leaves lifelong ugly scars, Buruli ulcer, which destroys the skin and soft tissues, and the sometimes fatal Chagas disease, an insect-transmitted illness that attacks the heart, oesophagus, colon and the peripheral nervous system. All four diseases are among the most neglected in the world. The people who suffer from them are almost all poor inhabitants of remote, rural areas.The new project will take a common approach to detecting, preventing and treating the diseases, actively seeking out people who show early symptoms and giving them effective treatment before the symptoms worsen.“The excellent results obtained by working together with WHO to combat sleeping sickness make us very confident that the same approach will produce similar results in other diseases,” sanofi-aventis President Jean-François Dehecq said. “With this new programme, we hope to contribute to saving many more lives and we are proud to be one of the major WHO collaborators to fight neglected tropical diseases.”Sanofi-aventis is the number 1 pharmaceutical company in France and in Europe. read more

Consumers need more disclosure about Internet speed claimsadvocacy group

AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to RedditRedditShare to 電子郵件Email OTTAWA – A new report says consumers need better disclosure from Internet providers about speed and performance claims.The report by an Ottawa-based advocacy group says Canadians have high expectations of advertised Internet speeds, but get little information from providers to judge actual speeds.The Public Interest Advocacy Centre’s report recommends the Competition Bureau consider specific enforcement guidelines on how advertising claims about Internet speeds are given to consumers.It also wants the CRTC to collect performance data on Internet speeds and compare them with advertised claims.The report says when a company advertises a maximum speed, consumers expect the maximum speed advertised will be achievable with their connection.It also says 75 per cent of those surveyed didn’t know which Internet speed tier they have, even though 83 per cent identified download speed as being important when choosing a provider. by The Canadian Press Posted Jan 23, 2013 4:58 pm MDT Consumers need more disclosure about Internet speed claims:advocacy group read more

Milwaukee Police Chief Fires Cop Over Social Media Posts

MILWAUKEE (AP) — A Milwaukee officer involved in the stun gun arrest of Bucks’ player Sterling Brown has been fired because of social media posts mocking the incident, the city’s police chief said Thursday.Police Chief Alfonso Morales said the firing decision was not tied to anything Erik Andrade did when Brown was arrested, but explained that the social media posts compromised the officer’s ability to testify in other cases. Morales spoke about the case at a Marquette University event.FILE – In this April 1, 2018, file photo, Milwaukee Bucks guard Sterling Brown is seen during an NBA basketball game in Denver. A Milwaukee police officer involved in the stun gun arrest of Bucks’ player Sterling Brown has been fired because of social media posts. (AP Photo/David Zalubowski, File)Brown sued the police department in June and accused officers of using excessive force and targeting him because he’s black. A group of officers swarmed on him at a Walgreens parking lot because he didn’t immediately remove his hands from his pockets. Brown was standing with the officers waiting for a citation for parking in a disabled spot early on Jan. 26, but never appeared to threaten police before or during his arrest, according to police body camera videos.Andrade later mocked Brown on Facebook for his arrest.“Nice meeting Sterling Brown of the Milwaukee Bucks at work this morning! Lol#FearTheDeer,” one Facebook post read, referencing a slogan used to cheer on the Bucks at games. Andrade also posted a racist meme of Golden State Warriors star Kevin Durant.Morales said in a statement that Andrade’s posts violate the department’s social media policies.“They have a racist connotation and are derogatory, mocking an individual who was recently the subject of officers’ use of force,” Morales said. “Such comments also directly affect his credibility and ability to testify in future hearings as a member of this Department. I have not, and will not, tolerate such behavior.”Andrade was at the scene when Brown was arrested but was not among the officers who took him down, according to police. A total of 11 officers involved in the arrest were disciplined or retrained, but Andrade was not among those punished at the time.The president of the Milwaukee Police Association, Mike Crivello, did not immediately respond to an email seeking comment on behalf of Andrade. Andrade does not have a listed phone number.Morales apologized to Brown for his officers’ actions and the Bucks’ second-year guard was never charged with anything. read more

Best practice in mineral processing

first_imgIndustry leaders agreed to two complementary strategies to drive forward best practice in mineral processing at the 2014 CEEC Workshop. Endorsing the work of the Global Mining Standards Group (GMSG), the Workshop delegates embraced the initiative led by the GMSG Industrial Comminution Efficiency team in generating global guidelines for standardised measurement of operating loads. Using standardised measurement processes will facilitate the generation of comparable data, essential to process optimisation.Additionally, the work of Dr Grant Ballantyne (The Julius Kruttschnitt Mineral Research Centre JKMRC) surveying the comminution energy requirements of gold and copper producing mines has provided reliable benchmarking data. This data can be used to compare comminution energy consumption across different mine sites. The comminution energy per unit metal product is presented in a graphical form similar to a cost curve.This simple technique allows individual mines to assess their current operational energy consumption against their peers. Anonymity of the comprehensive, mine-specific data is guaranteed and site to site variability is visualised by constructing an ‘energy curve’. The energy curve displays the potential energy savings and cost benefits of moving down the cost curve into more cost-efficient operating regimes. This approach also allows flexibility in the way comminution energy intensity is displayed (e.g. energy per rock milled or metal produced) thus providing a direct comparison between sites.The easily recognisable curve format can be used to visualise the variability in energy intensity across the industry. The applications of energy curves are many and varied.It can be used to map the position of the mine as production progresses with year-on-year analysisCircuit design proposals can be compared to current operational strategies to assess their benefitsOperational efficiency improvements can be mapped to the curve to visually assess the magnitude of energy efficiency gains per unit achievable through various strategiesThe efficiency with which the various comminution devices achieve size reduction can be mapped to identify opportunities for improvement and the magnitude of achievable gains.last_img read more

Touchscreen alternative uses a depth camera and thumb gestures

first_imgTouchscreens are now an integral part of any smartphone or tablet experience. And while interaction with them is getting better, they still present a problem due to one simple fact: in order to use them you have to cover part of the display.Masters student Christian Loclair may have a solution to that problem, but his main concern is minimizing the distraction caused by having to interact directly with a device. His research into this area of interaction for a thesis at the Hasso Plattner Institute has resulted in the development of alternative system based on single-hand thumb gestures.This new system is made possible by mounting a depth camera on a user’s chest that is capable of detecting both hand and finger movement. The user can use a thumb on the palm of their hand as if it is a touchscreen. Alternatively, a number of pinch gestures are supported for functionality such as scrolling a page or pressing a button.Such a system has both advnatages and disadvantages. It does keep a device’s display viewable during interaction, and it means you can hold your device in many different positions because you don’t need to interact with it directly. The disadvantages come in the form of the need for a depth camera, being forced to learn a whole new gesture system to use it, and the fact it won’t work in all situations, e.g. there’s no way this would be suitable for every game on the App Store.For the moment this remains an interesting, if complex alternative to the touchscreen. If it can be refined, or even act as a complimentary interaction technique to touchscreens, then it may make its way into a device. However, the big sticking point is going to be the requirement of having to wear a depth camera on your chest. More at Christian::Mio::Loclair, via Engadgetlast_img read more

Manuel Pellegrini insists Anderson can get better

first_imgWest Ham United manager Manuel Pellegrini insists Felipe Anderson will only get better after his brace against Southampton.The Brazilian joined the Hammers this summer from Lazio for a club record fee in the region of £35million, but took a while to settle into English football.Pellegrini demanded more from the 25-year-old at the start of this campaign, but with seven goals to his name, Anderson looks to be repaying the faith showed in him by West Ham.Pellegrini places a lot of responsibility on technical players and his faith in those players are starting to reap dividends, with the Hammers winning three of their last four games.Report: Rice is committed to West Ham not a United moveReport: Rice is committed to West Ham not a United move George Patchias – September 4, 2019 Declan Rice is committed to his West Ham contract and not a move to Manchester United.In an interview reported by, Rice opens up…The former Manchester City manager, however, insists he will continue to demand more from Anderson.“Of course he is a different player, a player that in every game makes important things,” Pellegrini said, according to Evening Standard.“I think he will continue improving. He still loses too many balls, maybe because he must understand the Premier League is difficult if you keep the ball in your feet.”“In every game he makes important plays and that’s the most great thing that he has.”last_img read more

South Dade Middle School teacher arrested for battery on officer child abuse

first_imgHOMESTEAD, FLA. (WSVN) – Police have arrested a South Dade Middle School teacher for battery on a law enforcement officer and child abuse with no harm.Miami-Dade County Public Schools said that 43-year-old Saryna Parker, a probationary teacher who has been at the school less than a year, will be fired.Police charged Parker with battery on a law enforcement officer and child abuse with no harm. Both charges are felonies.Parker appeared in court on Monday and was released from jail on $5,000 bond.Copyright 2019 Sunbeam Television Corp. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.last_img read more

NHTSA deepens investigation of 123 million airbags for potential defects

first_img Tags 2019 GMC Sierra Denali review: So close to greatness 2017 Chrysler Pacifica Hybrid: First hybrid minivan wins on fuel economy 26 Photos 2019 Chevrolet Corvette Grand Sport loves to hustle 2019 Jeep Cherokee can handle the rough stuff Honda Kia Hyundai Mitsubishi Toyota GMC CanyonIf you’re looking for a slightly fancier version of the Colorado that’s more focused on luxe than dirt, check out the GMC Canyon. The top Denali trim gets standard heated and ventilated front seats as well as a heated steering wheel. Maximum payload capability is 1,665 pounds while max towing is a fairly healthy 7,600 pounds.The Canyon is available with the same 2.5-liter four-cylinder engine, 3.6-liter V6 or 2.8-liter diesel as the Chevrolet Colorado. It’s also built in Wentzville, Missouri. Acura MDXMoving up one slot to sixth place on the American Made Index is the non-hybrid variant of the Acura MDX. With its SH-AWD system, the MDX is one of the better handling midsize luxury crossovers, and for 2019 the company gives us the A-Spec treatment with a new front fascia and side skirts, 20-inch wheels, wider exhaust tips, unique gauges, a new steering wheel, carbon fiber trim and various Alcantara interior touches.However, both the standard and A-Spec models get a 3.5-liter V6 engine, rated for 290 horsepower and 267 pound-feet of torque going through a nine-speed automatic transmission. The Acura MDX is made in East Liberty, Ohio.  Car Industry Enlarge ImageThe underlying alleged defect is wildly different from the problem that created the Takata scandal, but it could still impact crash safety nevertheless. Caspar Benson/Getty Images The mess of the Takata airbag-inflator scandal is still fresh in the automotive industry, but the National Highway Traffic Safety Administration has opened an investigation into a different airbag supplier, covering millions of parts across six different automakers.NHTSA announced this week that it has expanded an investigation into potentially defective airbags. The parts come from the supplier TRW, now known as ZF-TRW. There are 12.3 million such parts installed in cars with model years ranging from 2010 and 2019. Right now, these parts are installed in vehicles from Fiat Chrysler, Honda, Hyundai, Kia, Mitsubishi and Toyota. The regulatory body has not produced a full list of affected vehicles at this time.The potential issue stems from the supplier’s airbag control unit, which crunches sensor data to determine whether or not to deploy a vehicle’s airbags in the event of a crash. The control units, as NHTSA writes in its report, “may suffer electrical overstress due to harmful signals produced by the crash event.” In layman’s terms, this defect may cause the airbags to not deploy when they should.NHTSA’s report points out that Fiat Chrysler, Hyundai and Kia have all issued prior recalls for vehicles with this specific part. NHTSA’s Office of Defects Investigation also found two front crash events involving Toyota products with these parts. Thus, the agency has expanded its investigation to include not only the supplier, but also any manufacturer that has made use of the potentially faulty parts.Investigations are the first step in a process that could turn into a recall. If NHTSA finds that there is a serious problem that could affect vehicle and passenger safety, then it can compel suppliers and automakers to recall vehicles with the flawed parts.  Chevrolet CorvetteMoving up from the 10th-place slot last year is the 2019 Chevrolet Corvette. While we’ve all been ogling the new mid-engine Corvette, it’s easy to forget what a performance bargain the current-generation ‘Vette is. From the base trim to the Grand Sport to the bonkers ZR1, the Corvette is an American icon.My preference is for the Grand Sport, which strikes a perfect balance between everyday drivability and canyon-carving performance. The 6.2-liter V8 puts out 460 horsepower and 465 pound-feet of torque. You can get it with a seven-speed manual or eight-speed automatic transmission, but the kicker is the borrowed chassis and aero parts from the beefier Z06. Like I said, perfect balance. The Corvette is made in Bowling Green, Kentucky. 2019 Honda Odyssey offers plenty of room and features for families 81 Photos 2019 Acura MDX adds new features and an A-Spec model Tags 18 Photos Honda OdysseyThe feature-rich Honda Odyssey minivan also retains its number-two slot from last year’s list. While the 2019 model doesn’t see any changes from last, it’s still a darn good choice for families on the go with reconfigurable seats, Wi-Fi and an excellent rear-seat entertainment system. The Cabin Watch video system lets parents keep an eye on their little darlings without turning around in their seats, while Cabin Talk amplifies their voice so no yelling is required.The Odyssey is powered by a 3.5-liter V6 rated for 280 horsepower and 262 pound-feet of torque. Most trims get a nine-speed automatic but the top Touring and Elite trims now use a 10-speed automatic with stop-start technology. The Honda Odyssey is made in Lincoln, Alabama. 0 More From Roadshow Honda RidgelineAgain keeping the status quo, the Honda Ridgeline maintains third place on the American Made Index. This crossover-that-looks-like-a-truck provides a better ride than a traditional pickup and gets an awesome lockable trunk right in the floor of the bed. And it doesn’t do the truck stuff too badly, either, as it’s able to carry 1,860 pounds of payload and tow 3,500 pounds.The Ridgeline is powered by a 3.5-liter V6 good for 280 horsepower and 262 pound-feet of torque. That is channeled through a six-speed automatic transmission with available all-wheel drive. It’s built in Lincoln, Alabama. 2019 Toyota Prius AWD-e review: A thrifty hybrid with more grip 2019 GMC Canyon: A fancier Colorado Honda PassportThe Honda Passport is a new (well, reborn) entry to both the Honda lineup and the American Made Index. This midsize crossover comes to the fray with great driving dynamics and plenty of tech like the standard Honda Sensing suite of active safety features. An available 8-inch touchscreen gets Apple CarPlay and Android Auto as well as a Wi-Fi hotspot.Under the hood is the stalwart 3.5-liter V6 producing 280 horsepower and 262 pound-feet of torque. However unlike the Ridgeline, the Passport sends that power through a nine-speed automatic transmission. Having said that, just like the Ridgeline, this is the only powertrain available. The Honda Passport is built in Lincoln, Alabama. 2019 Maserati Levante GTS: Heart of gold Honda PilotDropping down to seventh place for 2019 is the Honda Pilot. Like its two-row Passport sibling, the three-row Pilot offers parent-focused technology like Cabin Talk as well as myriad standard driver-assistance features through the Honda Sensing tech suite. Honda’s largest crossover offers up nearly 84 cubic feet of cargo space. Honda’s 3.5-liter V6 engine shows up again, making a serviceable 280 horsepower and 262 pound-feet of torque. Touring and Elite trims get a nine-speed automatic transmission while lower trims have to make do with a six-speed auto. The Honda Pilot is made in Lincoln, Alabama. 68 Photoscenter_img 52 Photos Share your voice null General Motors Chevrolet Honda Jeep Acura 2019 Acura RDX A-Spec: Sharp handling, sharper looks 2019 Honda Ridgeline review: Light duty, heavy punch 2019 Chevrolet Colorado ZR2 Bison: A tougher off-roader Chevrolet ColoradoMaking its debut in the top 10 is the Chevrolet Colorado. Shown here in the tough ZR2 Bison off-road spec, the Chevy Colorado is an excellent truck and one of the two midsize pickups you can get with a diesel engine. Adding to the ZR2’s two-inch lift and front and rear locking differentials, the Bison gets beefier skid plates (trust me, that’s a good thing), steel bumpers and integrated recovery points. Heck, you can even get a snorkel.Base models get a 2.5-liter four-cylinder engine with a six-speed manual transmission, but a more popular choice is the 3.6-liter V6 gas engine with 308 horsepower and 275 pound-feet of torque, mated to an eight-speed automatic transmission. Meanwhile, the 2.8-liter diesel pumps out 186 horsepower and a delicious 369 pound-feet of twist and is mated to a six-speed automatic. The Chevy Colorado is built in Wentzville, Missouri. 2019 Chevy Colorado ZR2 Bison: An off-road animal 2019 Honda Pilot Elite: A smoother, tech-rich crossover SUV 12 Photos More From Roadshow 71 Photos Car Industry 0 69 Photos 2019 Honda Ridgeline: The commuter’s pickup truck Acura RDXThe third-generation Acura RDX squeaks into the top ten list with larger proportions, plenty of interior space and better handling than its predecessor. Forward collision warning with collision mitigation braking, adaptive cruise control that works even in low-speed traffic, lane-keeping steering assist and road departure mitigation are all standard across the board. Like its MDX counterpart, the RDX is available with the A-Spec styling package.The RDX sports a 2.0-liter, turbocharged, four-cylinder engine. Output is stated at 273 horsepower and 280 pound-feet of torque, and it’s mated to a 10-speed automatic transmission. The new RDX is built in East Liberty, Ohio. Fiat Chrysler Automobiles,Enlarge ImageIt’s all in a day’s work for the Jeep Cherokee, the most American-made car in 2019. Jeep With high trade tensions looming and increasing talk of tariffs, more and more consumers are looking to buy American. has released its annual American Made Index, showcasing companies that use the most American-sourced parts and labor in their vehicles. The results may surprise analyzed more than 100 US-built vehicles for five key data points: manufacturing location, parts sourcing, US employment, engine sourcing and transmission sourcing. You might think something like the Ford F-150 would top the list, but it drops from its No. 5 spot for 2018 and out of the top 10 completely. Even the first-place holder, the Jeep Cherokee, is a pretty global product. It’s a Jeep, sure, but that brand is part of Fiat Chrysler Automobiles, an Italian-owned surveyed 1,000 people and found that half are concerned about automotive import tariffs, with 41% saying they are unsure if tariffs would make them more likely to buy American. Either way, we’re big fans of all the vehicles on this list. These days, buying American doesn’t necessarily mean sticking with a US-based automaker. 49 Photos Jeep CherokeeKeeping its top-of-the-list placement, the Jeep Cherokee is 2019’s most American-made car. Refreshed for 2019, the compact crossover now features more tech, better cargo space and a slightly tweaked look. It’s available in no fewer the nine trims, including the off-road specific Trailhawk and a fancy-pants Trailhawk Elite.For 2019, the Cherokee gets a new 2.0-liter, turbocharged, four-cylinder engine with 270 horsepower and 295 pound-feet of torque, though naturally aspirated I4 and V6 choices are also available. Regardless of engine, a nine-speed automatic transmission gets the power to the pavement — or dirt as the case may be. The Cherokee is made in Belvidere, Illinois. Post a comment 2019 Honda Passport: A well-rounded midsize offering 10 Photos Share your voicelast_img read more

International Tiger Day 2019 Facts about the Big Cats

first_imgEvery year we celebrate International Tiger Day on 29 July. This day makes us aware of the declining numbers of big cats and to promote the work of their conservation.These facts will make us consider the importance of tiger conservation. 1. Tigers are the giant wild cats in the world. An adult tiger weighs up to 363kg. They are the third-largest carnivore on land after polar bears and brown bears. Also Read – This new drug can prevent Alzheimer’s Advertise With Us 2. Tiger’s natural habitats are Tropical rainforests, evergreen forests, temperate forests, mangrove swamps, grasslands and savannas. 3. Tigers like water. They are excellent swimmers and more often spend their time in pools or streams. 4. Tigers are the only cat species that are completely stripped. They even have stripes on their skin. Also Read – Hurricane heads for Florida after brushing Caribbean islands Advertise With Us 5. When it comes to female tigers, they are lovely. After a gestation period of more than three months, they give birth to two-three blind and helpless cubs and take care of them till they become independent at two years of age. 6. Unlike lions, Tigers do not live in permanent groups. They live private lives except when females are raising cubs. The correct name for the group of tigers is a “streak” or “ambush”. Advertise With Us 7. The average lifespan of a wild tiger is 10 – 15 years. Sometimes they are known to live up to 26 years in the wild. 8. There are five subspecies of tiger: Bengal, Indochinese, South China, Sumatran and Siberian. Miserably, three of them have become vanished – Caspian, Bali and Javan. 9. The fossil remains of tigers found in China are supposed to be 2 million years old. 10. Less than a century back, tigers were all over Asia. However, the population is at risk due to hunting and habitat loss.last_img read more

Will Jaitleys thumbs up to blockchain lead to govts own cryptocurrency

first_imgFinance Minister Arun Jaitley said on Thursday that the cryptocurrency is not a legal tender in India.Creative CommonsThe Narendra Modi-led  NDA government reiterated its stand on cryptocurrencies as finance minister Arun Jaitley said in his Budget speech on Thursday that digital currencies are illegal in India, and that the government was not going to recognise them.The move is seen as an effort to control the proliferation of cryptocurrencies by the government, which has repeatedly warned investors in the country against the dangers of investing in digital currencies like Bitcoin. Jaitley’s comments, however, didn’t come as a surprise since the government was expected to announce measures to regulate cryptocurrency in India.”Cryptocurrencies are not legal tender and the government discourages its use. However, the government will look at the utilisation of blockchain,” Jaitley said in his Budget speech in Parliament, adding that the technology can help further boost the Digital India campaign. The Great India BudgetIBTimes IndiaAlthough the finance minister didn’t provide any details about how the government is planning to utilise the blockchain technology, industry experts believe that its adoption can be encouraging for the micro, small and medium enterprise (MSME) sector.”The government’s decision to explore the usage of blockchain technology, a shared digital ledger which has been fast finding favour with financial intermediaries, will help ease credit flows to MSMEs since it can track and record each and every transaction of individuals and enterprises on a shared network,” Vinay Kalantri, founder and managing director of The Mobile Wallet, told International Business Times, India in an email statement.The government’s decision to adopt the blockchain technology has also sparked fresh speculation that the Reserve Bank of India (RBI) could eventually consider having its own cryptocurrency.The central bank, which is apparently uncomfortable with the non-fiat nature of the conventional virtual currencies, is already said to be looking at the possibility of a fiat cryptocurrency that can become the digital counterpart of the Indian rupee. Some experts also believe that the government is not entirely averse to cryptocurrencies.”The announcement on the cryptocurrency by the FM should not be misinterpreted to mean the cryptocurrency is going to be discouraged by the Government. The intention is more likely to regulate the circulation to avoid its use for illegal transactions,” Rashmi Deshpande, associate partner, Khaitan & Co, told IBTimes India, in an email statement. Is Bitcoin really a bubble?Creative CommonsHowever, the future of cryptocurrency exchanges remains uncertain in India. Some recent reports have revealed that several banks had frozen accounts of such exchanges in the country while the Registrar of Companies (ROC) had stopped registering companies that intended to act like cryptocurrency exchanges.”Businesses engaged in this will have to evaluate future prospects, but it has always been uncertain how Indian conservative monetary and fiscal policies will view this alternate form of currency,” said Sameer Sah, associate partner, Khaitan & Co.Thanks to the rise and rise of Bitcoin in 2017, cryptocurrencies have gained immense popularity globally over the past few months. However, the so-called Bitcoin craze has also come under government’s scrutiny as it can be used to evade tax or lure unwary investors to put money into Ponzi schemes.There have also been several instances when cyber attackers have hacked into investors’ accounts to steal a huge amount of money. A successful implementation of blockchain or paving way for RBI’s own cryptocurrency, therefore, require more clarification on several factors ranging from the KYC and transferability to ownership and security.”It will be important to understand the investment and longer-term strategic thinking that this new technology will demand from the Central Government,” J A Chowdary, special chief secretary and IT advisor to the chief minister of Andhra Pradesh, told IBTimes India.”The government must deliberate the use of blockchain for smart contracts and blockchain-based KYC which will bring security, efficiency, and speed to a wide range of services and processes,” Chowdary, who is also the chairman and group CEO of Andhra Pradesh Electronics and IT Agency, added.last_img read more

Odd couple at 1st summit

first_imgA combination of file photos showing Chinese President Xi Jinping (L) and US President Donald Trump. Reuters file photoWhen US President Donald Trump meets Chinese President Xi Jinping this week, their summit will be marked not only by deep policy divisions but a clash of personalities between America’s brash “tweeter-in-chief” and Beijing’s cautious, calculating leader.They may have one thing in common: their rhetoric about restoring their nations to greatness. But the two men differ in almost every other respect, from their political styles to their diplomatic experience, adding uncertainty to what has been called the world’s most important bilateral relationship.Five months after his election on a stridently anti-China platform, Trump appears to have set himself on a course for collision rather than conciliation with Xi, raising doubts as to whether the world’s two biggest economies can find common ground.Topping the agenda at Trump’s Mar-a-Lago resort in Florida will be whether he will make good on his threat to use crucial US-China trade ties to pressure Beijing to do more to rein in its nuclear-armed neighbor North Korea, which is working to develop missiles capable of hitting the United States.Trump, a 70-year-old former real estate magnate with no foreign policy experience before entering the White House, has tweeted that it will be a “very difficult” meeting with the veteran Communist Party leader seven years his junior, given Chinese trade practices he says are killing US jobs.He has also demanded that Beijing do more to “solve” the North Korean problem – his biggest national security challenge – or he will act alone to deal with Pyongyang’s nuclear and missile programs.Some White House aides believe Trump’s son-in-law and senior adviser Jared Kushner could be an influential moderating voice on how he handles Xi in their talks on Thursday and Friday. Contacts between Kushner and China’s US envoy helped smooth the way for the meeting, according to current and former US officials.Even so, what worries the protocol-conscious Chinese more than policy clashes is the risk that the unpredictable Trump could publicly embarrass Xi, after several foreign leaders experienced awkward moments with the new US president.“Ensuring President Xi does not lose face is a top priority for China,” a Chinese official said.US presidents’ meetings with their Chinese counterparts are usually more tightly scripted than with other foreign leaders, something Chinese officials insist on to make sure they are treated with the decorum they believe befits a global power.This summit should offer a study in contrasts: Trump impatient, outspoken and prone to angry tweet-storms; Xi, outwardly calm and measured, with no known social media presence.Their shared nationalist tendencies could aggravate friction between their countries, which are increasingly global rivals.Trump insists the United States has been cheated economically for decades by countries like China and must regain its luster, while Xi wants China, once an ancient empire, to be able to flex its muscles on the world stage.“Xi and Trump are not natural friends,” said a former senior US official specializing in Asia. “The question is when Trump’s ‘Make America Great Again’ hits Xi’s ‘Chinese Dream’, what’s the result?”WON’T PULL PUNCHESIt remains unclear how far Trump will go in translating populist rhetoric into policy that steps up pressure on China, given the risk of a trade war neither country can afford.But aides say he won’t pull his punches, especially on trade, on which he has held an outspoken view for decades.This adds to doubts as to whether the two leaders can find common ground on North Korea and China’s expansive claims in the South China Sea.Some analysts question whether Trump can get the better of Xi, who was born into a life of politics and has a reputation for being a tough tactician.“Xi’s performed pretty well in these types of environments,” said Christopher Johnson, a China expert and former CIA analyst at Washington’s Center for Strategic and International Studies.While Trump has been in office little more than 10 weeks, Xi has honed his US strategy since assuming the Chinese leadership in 2013.The son of a revolutionary leader, Xi has sought to project the image internationally of a strong advocate of globalization at a time when Trump has stoked fears of US protectionism.Still, Chinese officials are mindful of the pitfalls if Trump veers off-script.Japanese Prime Minister Shinzo Abe found himself in a long, uncomfortable handshake at the White House in February, and Trump appeared to ignore German Chancellor Angela Merkel’s offer of a handshake during their meeting last month.An acrimonious call between Trump and Australian Prime Minister Malcolm Turnbull caused particular concern in Beijing, officials there say.Still, the decision to hold a summit so early in Trump’s presidency suggests both Washington and Beijing see the value of trying to build a personal relationship between the two leaders.Trump goes into the meeting with significant gaps in his team of Asia advisers and his China policy still not fully formulated.Hardliners like trade adviser Peter Navarro, who authored a book “Death by China,” have feuded over the administration’s approach to China with more pragmatic aides such as economic adviser Gary Cohn, a former Goldman Sachs president, current and former US officials say.Administration officials argue Trump can use his “Art of the Deal” sales techniques to convince Xi that China needs the United States more than the United States needs China, especially when it comes to market access.But analysts say the Chinese are shrewd enough at geopolitics to fend off US demands. Xi may also see Trump politically weakened by his high-profile legislative failure on healthcare as well as his low public approval ratings.Trump has already backed down on China’s most sensitive issue – Taiwan – having first infuriated Beijing by suggesting he might not abide by Washington’s long-standing “one China” policy. Trump may now feel he is owed a favor in return.A fence-mending phone call in February was arranged by Kushner and China’s US ambassador, Cui Tiankai, officials say, after Cui invited Trump’s daughter Ivanka to the Chinese Embassy’s Lunar New Year reception, where her daughter sang in Mandarin.Both sides are keeping expectations low for tangible outcomes from the summit, billed as informal “get to know you” meetings similar to the 2013 Sunnylands summit in California between Xi and Trump’s predecessor, Barack Obama.And whatever else, unlike Abe’s February visit to Mar-a-Lago, there will be no golf diplomacy: China’s Communist Party associates golf with shady dealings and has sought to stop officials from playing it as part of Xi’s fight against corruption.last_img read more

Biotechnology Using wireless power to light up tiny neural stimulators

first_img © 2019 Science X Network Controlling neurons with light—but without wires or batteries , Science For this, the team coupled a microscale light-emitting diode (LED) with two millimeter-scale coils to create an inductive charging system, which delivered instantaneous power at biologically safe frequencies in an experimental rodent (rat) model. The wireless setup stimulated neurons in the visual cortex, while maintaining the temperature increase below 10C as a critical safety threshold for biomedical implants. The results are now published on Microsystems and Nanoengineering. Khan et al. introduced a single channel neurostimulator containing a reflector-coupled, microscale light-emitting diode (µLED) with an integrated millimeter sized wireless receiver (RX) coil. The experimental setup allowed for free-floating, battery-free, untethered optogenetics neuromodulation. They used a two-coil inductive link in the system to deliver instantaneous power at a low operating frequency (<100 MHz) for continuous optical stimulation. The process posed minimal invasiveness and tissue exposure to electromagnetic radiation. When they coupled a microscale reflector to the µLED, the optical-reflector displayed significantly enhanced light intensity compared to bare µLED. The scientists controlled the operational temperature of the setup for implant biocompatibility and conducted in vivo experiments in rats, followed by histological studies to verify the efficacy of wireless optical stimulation in the primary visual cortex of the animal model. They visualized the process using c-Fos biomarker, which appeared green on immunostaining, as a reporter of light-evoked neuronal activity. TOP: Simulation model for the inductive coupling at cross-section planes. Plane 3 refers to the bottom plane of the Tx coil (z axis displacement, z = 0), plane 1, 2, 4 refers to z = 2.5 mm, z = 1 mm, and z = −1 mm, respectively. (a) The simulation model in HFSS. Magnetic flux distributions for (b) plane 1, (c) plane 2, (d) plane 3, and (e) plane 4. Induced magnetic flux by the Rx coil at plane 2, while the Rx is positioned at f Tx center and g Tx periphery. Units of flux distributions provided in the color map legend. BOTTOM: Optical and thermal characteristics. (a) Light penetration through tissue sections with a coupled reflector (n = 5), (b) intensity improvement of reflector coupled stimulator compared with a bare μ-LED, and (c) change in temperature for devices stimulating through a 500 μm cortical tissue slice (n = 3). Credit: Microsystems & Nanoengineering, doi: 10.1038/s41378-019-0061-6 System validation using Immuno-histology. (a) In vivo stimulation using a wirelessly-powered neurostimulator on the V1 of an anaesthetized rat. (b) quantitative representation of c-Fos expressed cells using cell sorting. Fluorecent images of mCherry (c, e) as well as c-Fos (d, f) expressions of the control and stimulated cortices, respectively, obtained from the same cortical areas of the same transfected animal. (g, h) c-Fos expressions of the control and stimulated cortices, respectively, obtained from a non-transfected animal. Credit: Microsystems & Nanoengineering, doi: 10.1038/s41378-019-0061-6 Discoveries and inventions in neuroscience have recently progressed rapidly due to advances in semiconductor implants in neurobiological systems, for successful clinical translation. For example, scientists can use implantable "electroceuticals" in a new medical approach to target the central and peripheral nervous system during therapeutic intervention. As a result, optogenetics is finding new applications in neuroscience to deliver light to neural tissues of interest while collecting readouts from cells using targeted control tools. The ability to implant miniature optical sources, recording electrodes, sensors and other components in to designated areas of the brain has renewed the optimism for long-term diagnostics and therapeutics. Using such developments, scientists can study the transmission of primary sensory information to specific domains of the brain, including the olfactory, visual and auditory regions in depth. They can also use the technique to understand cells that drive or inhibit fundamental bioactivities such as hunger, thirst, energy balance and respiration via activity patterns. , Nature Methods Conceptual diagram of the wirelessly-powered opto neuro-stimulator and its placement over the cortex of the animal (rodent) brain. Credit: Microsystems & Nanoengineering, doi: 10.1038/s41378-019-0061-6 Explore further "" The scientists then conducted in vivo experiments in transfected rats (foreign DNA introduced into cells) to then implement the proposed surgical procedures. They followed the experiments with immunohistochemical assays to validate the efficacy of the cell transfection procedure and the subsequent optical stimulation procedure in the rats. During transfection, they induced the expression of channelrhodopsin-2 in the animal models with a viral solution and then placed the coiled stimulator on the primary visual cortex (V1 lobe) of the animal for subsequent optical stimulation. The scientists coupled the coiled stimulator to a Tx coil and used the other V1 lobe of the same animal as a control sample. After completing the in vivo experiments, the scientists analyzed the expression of c-Fos (green dye) in the stimulated vs. non-stimulated lobe to identify neural activity. For this, Khan et al. used immunobiological assays in the work and observed elevated c-Fos expression (green) within the virus-transfected cortex (red) induced by LED stimulation of the experimental neurostimulator. In this way, Khan et al. designed, fabricated and characterized a reflector-coupled, wireless single-channel optical neurostimulator with a mm-sized receiver coil for optogenetic neuromodulation. The reflector-coupled stimulator allowed higher performance compared to bare µLED in the present work. The scientists studied the performance of the two-coil telemetry link using analytical circuit models, FEM stimulations and experimental approaches. They verified the proposed potential of the neurostimulator in a rat model with upregulated cellular activity observed via optical stimulation. Khan et al. will aim to conduct further investigations in the future to miniaturize the devices for neurobiological applications. The scientists tested the surface morphology of the prototype using scanning electron microscopy to observe the cavity array after isotropic silicon etching and surface aluminum coating. They then tested the surface roughness using atomic force microscopy to detect surfaces that created negligible light scattering for optimally enhanced light intensity and activated the neurostimulator on a benchtop setup via inductive powering. The scientists also incorporated Parylene-c to engineer the constructs due to inherent biocompatibility of the material, although they observed potential cracking as before as a result of high temperatures in the engineering process. Khan et al. simulated electromagnetic properties of the inductive link between the Rx and Tx coils using the finite element method (FEM) and high frequency structure stimulator (HFSS) software; to show similarities between the simulated Tx coil and those engineered in the work. The scientists investigated the optical properties and showed that the neurostimulator could reach deep brain cells less invasively compared to a waveguide or penetrating probes. While the data showed superior optical performance of the reflector-coupled stimulator, the intensity reduced heavily with thicker tissue sections. The intensity of the reflector-coupled stimulator was significantly higher in the present work compared with a bare stimulator for effective deep brain stimulation without deep-brain tissue invasion. Khan et al. similarly tested and optimized the thermal properties, electromagnetic properties and the power transfer efficacy of the neurostimulator prototype. To conduct translational studies in an animal model, the scientists proposed implanting the resonator coil between the skull and skin without wire connections to the Tx or Rx coil. Optogenetics must target the neural population without altering the natural behavior of animal models for accurate applications in medicine. Pioneering work by researchers in the field have led to the development of several optimized neuro-stimulators with mid-field radiofrequency (RF) and far-field power transfer. However, scientists are yet to report on a fully implantable and miniaturized high voltage (HV) stimulator that provides precise stimulation control of the parameters of interest. An ideal wireless optical implant must therefore:Be miniature in the millimeter scale (mm) to prevent invasive surgical infection, inflammation and post-surgical trauma.Allow highly efficient power transfer and long-distance communication to deep region target neurons with aims for human applications.A significant challenge with engineering such implants is the energy required to optically activate optogenetic opsins, which typically include a few mWs, although greater than the values for conventional electrical stimulation or data communication. To solve this challenge, Khan and co-workers proposed a fully implantable, mini wireless optical stimulator to deliver sufficient power for µLED operations—without surpassing the operational temperature. In the proposed system, they included a solenoid transmitter (TX) coil and receiver (RX) unit. In a proof-of-concept of the proposed prototype, Khan et al. used a blue µLED (465 nm wavelength) of 270 µm x 220 µm surface area to optically excite neurons expressing channelrhodopsin. To validate the functionality of the device in an animal model, the scientists placed the Tx coil outside the brain and inductively coupled it to the Rx coil, which was integrated to the µLED neurostimulator placed within a craniotomy cavity. The scientists used the free-floating method for epidural optical neuromodulation in the craniotomy cavity located on top of the dura mater. Citation: Biotechnology: Using wireless power to light up tiny neural stimulators (2019, June 10) retrieved 18 August 2019 from More information: Wasif Khan et al. Inductively coupled, mm-sized, single channel optical neuro-stimulator with intensity enhancer, Microsystems & Nanoengineering (2019). DOI: 10.1038/s41378-019-0061-6 Kristoffer Famm et al. A jump-start for electroceuticals, Nature (2013). DOI: 10.1038/496159a Karl Deisseroth. Optogenetics, Nature Methods (2010). DOI: 10.1038/nmeth.f.324T.-i. Kim et al. Injectable, Cellular-Scale Optoelectronics with Applications for Wireless Optogenetics, Science (2013). DOI: 10.1126/science.1232437 Conceptual diagram of the inductively coupled neuro stimulator system. (a) An overview of the inductive link system. (b) Conceptual diagram of the wirelessly-powered opto neuro-stimulator and its placement over the cortex of the animal brain. Credit: Microsystems & Nanoengineering, doi: 10.1038/s41378-019-0061-6 Characterization results and images of an operating prototype. (a, b) SEM images of the etched Si cavity. (c, d) Post and prior Al coating of the cavity, respectively. (e, f) AFM images for quantitative analysis of cavity surface roughness (x axis units in μm, y axis in nm). (g) Fabricated single-channel opto neurostimulator. h Rx-coil coupled single-channel opto neurostimulators. (i, j) An opto stimulator powered wirelessly by a Tx coil. Credit: Microsystems & Nanoengineering, doi: 10.1038/s41378-019-0061-6 Journal information: Nature This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Implantable optical devices that target neurons can be improved using miniature coils smaller than a grain of rice using optogenetic technology. Scientists can propagate pulses of light using the method to turn protein expression on or off in genetically modified neurons. Neuroscientists have used bulky cables and batteries to control and collect data from such experimental setups so far. In a recent study, Wasif Khan and a team of researchers in the interdisciplinary departments of Electrical and Computer Engineering and Physiology in the U.S. developed a completely wireless prototype to replace the bulky hardware.last_img read more